Introduction
Welcome to the 8^th Annual International Physiology of Pacing Symposium, a gathering of world-renowned faculty who delve into the latest methods and strategies for optimizing the physiological pacing of the heart. This one-day CME-accredited symposium will focus on cutting-edge conduction system pacing (CSP) approaches, including His-bundle Pacing (HBP), left bundle branch area pacing (LBBAP), and left ventricular septal pacing (LVSP). These evolving pacing modalities hold immense potential to achieve electrical excitation of the heart through the normal specialized conduction system.

By participating in the symposium, clinicians will not only gain a comprehensive understanding of the history and relevant anatomy of the conduction system, particularly about HBP/LBBAP/LVSP, but also acquire practical knowledge that can be immediately applied in their clinical practice. The program will also provide an overview of established clinical applications and ongoing clinical trials, equipping clinicians with the latest advancements in the field and empowering them to enhance their patient care.

Register >>

Date
Friday, October 25, 2024

Location
Crystal Gateway Marriott, 1700 Richmond Highway, Arlington, Virginia

Two Attendance Options • In-Person or Virtually in Real-Time
The 8^th Annual International Physiology of Pacing Symposium offers two attendance options, designed to accommodate your preferences and needs. You can choose to attend in person at the Crystal Gateway Marriott, or virtually via a Real-Time Live Stream. Both onsite and virtual attendees are eligible to claim CME credits.

**Attention Fellows and Residents**
Fellows and Residents whose onsite attendance has been confirmed will be refunded their registration fee during check-in.

Abstract Competition
Share your Research with Colleagues and Leading Experts!
Please submit your abstract of original research for the opportunity to present it at the 8th Annual International Physiology of Pacing Symposium during the New Science Abstract Presentation Session Learn More >>

Agenda

Agenda Times Listed Are Eastern Standard Time Agenda and Faculty Subject to Change
6:30 – 7:25 AM		Breakfast and Exhibits
7:25 – 7:30 AM		Welcome and Introductions
		Session I Anatomy and Physiology of the Conduction System *Chairs:* Kenneth Ellenbogen, MD and Roderick Tung, MD
7:30 – 7:40 AM		3-D Anatomy of the Conduction System Kalyanam Shivkumar, MD, PhD
7:40 – 7:50 AM		3-D Activation Assessment in Conduction System Pacing vs. BVP – Comparing HBP, LBBP, LVSP, and BVP Zachary Whinnett, MD
7:50 – 8:00 AM		R-Wave Peak Times in lateral leads (V5, V6, aVL): Relevance to Conduction System Capture and Site of Pacing Marek Jastrzebski, MD
8:00 – 8:10 AM		Hemodynamics of LBBP vs. LVSP: Does LBB Capture Matter? Justin Luermans, MD
8:10 – 8:20 AM		Hemodynamics of Biventricular Pacing – Endocardial vs. Epicardial Pacing: Learnings from Wise-CRT Vivek Reddy, MD
8:20 – 8:30 AM		Panel Discussion: “How Does Pacing Site Impact Electrical Activation Pattern and Hemodynamics?”
8:30 – 9:30 AM		Session II Live Cases: Bradycardia *Moderator:* Pugazhendhi Vijayaraman, MD *Panelists:* Parikshit Sharma, MD, and Weijian Huang, MD Live Case: Conduction System Pacing in Bradycardia *Live Case Site:* Geisinger Medical Center Live Case Operators: Jess Oren, MD, and Faiz Subzposh, MD Live Case: LBBP in Bradycardia *Live Case Site:* Hospital of the University of Pennsylvania *Live Case Operator:* Robert Schaller, DO and Colleagues
		Session III Physiologic Pacing in Bradycardia *Chairs:* Gopi Dandamudi, MD and Gaurav Upadhyay, MD
9:30 – 9:40 AM		HBP for Bradycardia Pacing: When and Why Would You Use? Haran Burri, MD
9:40 – 9:50 AM		Continuous Pacing to Facilitate Left Bundle Branch Capture Assessment During LBBAP Marek Jastrzebski, MD
9:50 – 10:00 AM		Reducing the Risk of Pacing Induced Cardiomyopathy – Rationale for BVP vs. CSP vs. RVP for Patients with Advanced AV Block Suneet Mittal, MD
10:00 – 10:10 AM		LBBAP (LBBP vs. LVSP) in AV Block: Implications for Pacing-Induced Cardiomyopathy? Gopi Dandamudi, MD
10:10 – 10:20 AM		UHF-ECG and Lessons Learned Regarding LV Synchrony Kevin Vernooy, MD, PhD
10:20 – 10:30 AM		Panel Discussion: CSP vs. RVP vs. BVP in Narrow QRS Patients with AV Block
10:30 – 10:40 AM		Break and Exhibits
		Session IV Physiologic Pacing and Cardiac Resynchronization Therapy I *Chairs:* Pugazhendhi Vijayaraman, MD, and Kenneth Ellenbogen, MD
10:40 – 10:50 AM		Irregulapathy: Rationale for AVN Ablation and CSP Jacqueline Joza, MD
10:50 – 11:00 AM		Left Ventricular Fusion Pacing Algorithms and/or AV Optimization to Improve CRT Response? Michael Gold, MD
11:00 – 11:10 AM		When Should CSP Be the First-Line Therapy for CRT and Why? Parikshit Sharma, MD
11:10 – 11:20 AM		Confirming LBB Capture During CRT: Limitations of Current Criteria Pugazhendhi Vijayaraman, MD
11:20 – 11:30 AM		MRI for Selection of Optimal CRT in Patients with LBBB-Associated/Induced Cardiomyopathy Shunmuga Sundaram Ponnusamy, MD
11:30 – 11:40 AM		Leadless Pacing: Dual chamber to CSP - Aveir DR, Micra AV2, Revolution, Wise-CRT or Newer Tools - Implications for CSP Vivek Reddy, MD
11:40 – 11:50 AM		Device Therapy for RBBB and Heart Failure: What Should We Do? Valentina Kutyifa, MD
11:50 – 12:00 PM		Panel Discussion: CSP vs. BVP in CRT
12:00 PM – 12:30 PM		Lunch and Exhibits
12:40 – 1:40 PM		Session V Live Cases: CRT *Moderators:* Pugazhendhi Vijayaraman, MD, Kenneth Ellenbogen, MD, and Roderick Tung, MD Live Case: CSP using Lumenless Lead for CRT *Live Case Site:* Geisinger Medical Center *Live Case Operators:* Atiqa Batul, MD, and Jess Oren, MD Live Case: CSP Using Stylet-Driven Lead for CRT *Live Case Site:* Hospital of the University of Pennsylvania *Live Case Operator:* Robert Schaller, DO and Colleagues
		Session VI Physiologic Pacing and Cardiac Resynchronization Therapy II *Chairs:* Gopi Dandamudi, MD, and Mina Chung, MD
1:40 – 1:50 PM		Optimizing CRT in RBBB Patients: Role for CSP Roderick Tung, MD
1:50 – 2:00 PM		IVCD or LBBB or Mixed Conduction Disease: Musings from ECG, HBP, Left Septal Mapping Gaurav Upadhyay, MD
2:00 – 2:10 PM		CRT in IVCD – Rationale for HOT/LOT CRT or BVP Haran Burri, MD
2:10 – 2:20 PM		CSP: Implications and Potential for Arrhythmia Prevention Bengt Herweg, MD
2:20 – 2:30 PM		LBBP vs. LVSP for CRT in LBBB – How Important is Conduction System Capture? Weijian Huang, MD
2:30 – 2:40 PM		Stylet Driven Leads for CRT – Evidence, advantages and Limitations Francesco Zanon, MD
2:40 – 2:50 PM		Panel Discussion: LBBAP and Limitations
2:50 – 3:00 PM		Break and Exhibits
		Session VII Novel CIED Options for Heart Failure *Chairs:* Roderick Tung, MD, and Valentina Kutyifa, MD, PhD
3:00 – 3:10 PM		Bachmann’s Bundle Pacing: How to Perform and Rationale for Prevention of AF Daniel Lustgarten, MD
3:10 – 3:20 PM		Heart Failure with Preserved Ejection Fraction: MyPace and Beyond Markus Meyer, MD, PhD
3:20 – 3:30 PM		Cardiac Contractility Modulation (CCM) – Where Do We Stand in 2024? Niraj Varma, MD, PhD
3:30 – 3:40 PM		Autonomic Neuromodulation for Heart Failure Gaurav Upadhyay, MD
3:40 – 3:50 PM		Device selection for treatment of HF: What do the HRS Guidelines Recommend? Mina Chung, MD
3:50 – 4:00 PM		Panel Discussion
		Session VIII Durability, Follow-Up, and Trial Updates *Chairs:* Jacqueline Joza, MD, and Parikshit Sharma, MD
4:00 – 4:10 PM		Remote Monitoring and Use of Cloud-Based Providers for CIED Follow-Up – How to Maximize RM for CSP? Suneet Mittal, MD
4:10 – 4:20 PM		Lead Failure in LBBAP: (Loss of Conduction Capture, Lead Fracture, etc.) Evidence and Bench Testing Parikshit Sharma, MD
4:20 – 4:30 PM		Pearls for Follow-Up for CSP Devices Haran Buri, MD
4:30 – 4:40 PM		Ongoing CSP Trials Mihail Chelu, MD, PhD
4:40 – 5:20 PM		New Science Abstract Presentations Chairs: Kenneth Ellenbogen, MD, and Pugazhendhi Vijayaraman, MD Global R-wave Peak Time (RWPT) Is More Diagnostically Accurate Than V6 RWPT and Insensitive to Variations in Paced QRS Morphology and Axis Grzegorz Kielbasa, MD First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University Medical College, Kraków, Poland LOCAlizaTion and Clinical CorrElation of Left Bundle Branch Pacing lead (LOCATE LBBP) – Insights from a Computed Tomographic Angiography Study Shunmuga Sundaram Ponnusamy, MD, DM Velammal Medical College Hospital and Research Institute, Madurai, India Predictors of Efficacy of His Bundle Pacing: A Stratified Analysis of the HOPE-HF RCT Nandita Kaza, MBChB Imperial College London, London, United Kingdom
5:20 PM		Industry Presentations and Cocktail Reception Abbott: Leonard Ganz, MD Biotronik: Bobak Salehi Boston Scientific: Jonathon Weinstock, MD Medtronic: Robert Kowal, MD

Partner Institutions

Co-Sponsor

Faculty

Course Directors

Gopi Dandamudi, MD
Prisma Health
Greenville, SC

Kenneth Ellenbogen, MD
VCU School of Medicine
Richmond, VA

Roderick Tung, MD
Banner University Medical Center- Phoenix
Phoenix, AZ

Gaurav Upadhyay, MD
The University of Chicago Medicine
Chicago, IL

Pugazhendhi Vijayaraman, MD
Geisinger Wyoming Valley Medical Center
Danville, PA

Faculty

Atiqa Batul, MD
Geisinger Medical Center
Danville, PA

Haran Burri, MD
University Hospital of Geneva
Geneva, Switzerland

Mihail Chelu, MD, PhD
Baylor College of Medicine
Houston, TX

Mina Chung, MD
Cleveland Clinic
Cleveland, OH

Michael Gold, MD, PhD
Medical University of South Carolina
Charleston, SC

Bengt Herweg, MD
University of South Florida Morsani College of Medicine
Tampa, FL

Weijian Huang, MD
The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, China

Marek Jastrzebski, MD
Jagiellonian University Hospital
Krakow, Poland

Jacqueline Joza, MD
McGill University Health Centre
Montreal, Québec, Canada

Valentina Kutyifa, MD, PhD
University of Rochester
Rochester, NY

Justin Luermans, MD
Maastricht University Medical Center
Maastricht, The Netherlands

Daniel Lustgarten, MD
University of Vermont Medical Center
Burlington, VT

Markus Meyer, MD, PhD
Lillehei Heart Institute, University of Minnesota
Minneapolis, MN

Suneet Mittal, MD
Valley Health System
Ridgewood, NJ

Jess Oren, MD
Geisinger Medical Center
Danville, PA

Shunmuga Sundaram Ponnusamy, MD
Velammal Medical College Hospital and Research Institute
Madurai, India

Vivek Reddy, MD
The Mount Sinai Hospital
New York, NY

Robert Schaller, DO
Hospital of the University of Pennsylvania
Philadelphia, PA

Parikshit Sharma, MD
Rush University Medical Center
Chicago, IL

Kalyanam Shivkumar, MD, PhD
UCLA Cardiac Arrhythmia Center
Los Angeles, CA

Faiz Subzposh, MD
Geisinger Medical Center
Danville, PA

Niraj Varma, MD, PhD
Cleveland Clinic
Cleveland, OH

Kevin Vernooy, MD, PhD
Maastricht University Medical Center
Maastricht, The Netherlands

Zachary Whinnett, MD
CA Healthcare UK
Imperial College NHS Trust
London, United Kingdom

Francesco Zanon, MD
Santa Maria della Misericordia Hospital
Rovigo, Italy

CME Accreditation

Target Audience
This educational activity is designed for electrophysiologists, general cardiologists, electrophysiology fellows in training, and allied healthcare professionals.

Learning Objectives
Upon completion of this educational activity, participants will be able to:

Discuss the evolving role of conduction system pacing (CSP) for standard permanent pacing and cardiac resynchronization.
Describe challenges and methods for implantation technique of permanent His-bundle pacing (HBP), left bundle branch area pacing (LBBAP), and left ventricular septal pacing (LVSP)
Review the relationship between electrical stimulation of the heart and the mechanics of myocardial contraction.
Review the history and recent advances of CSP and emerging clinical situations and applications in patients with narrow and wide QRS morphology.
Review the anatomy of the membranous septum conduction system concerning the right atrium, tricuspid valve, and ventricular septum.
Summarize strategies and clinical evidence for the various approaches to achieve cardiac resynchronization, including leadless technology, multisite pacing, and left ventricular (LV) endocardial pacing.
Outline approaches to complications during implant procedures for CSP.
Discuss approaches for remote monitoring and optimization of CSP and CRT systems.

Accreditation Statement
Jointly Accredited Provider TM MediaSphere Medical and Ciné-Med have planned and implemented this activity to improve patient care. Ciné-Med is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Ciné-Med designates this educational activity for a maximum of 9.5 AMA PRA CATEGORY 1 Credit(s)™.
Physicians should only claim credit commensurate with the extent of their participation in the activity.

Ciné-Med designates this activity for 9.5 Contact Hours for Nurses.

Claiming Credits
The 8^th Annual International Physiology of Pacing Symposium is CME-accredited for onsite and virtual attendees. Physicians may claim CME Credits or Contact Hours for Nurses directly on this webpage at the conference's conclusion. 1 CME Certificate is supplied electronically for the cumulative credits earned commensurate with the extent of participation in the activity.

Disclosure Policy
MediaSphere Medical and Ciné-Med adhere to accreditation requirements concerning industry support of continuing medical education. Speakers must openly disclose any data limitations and/or discuss any off-label, experimental, or investigational uses of drugs or devices in their presentations. Speakers will disclose any relationships at the beginning of their presentations.

All MediaSphere Medical and Ciné-Med employees in content control have indicated that they have no relevant financial relationships to disclose.

MediaSphere Medical and Ciné-Med policy is to ensure balance, independent objectivity, and scientific rigor in all supported educational programs. All faculty members participating in academic activities must disclose to the program audience any real or apparent conflicts of interest held within the past 12 months.

MediaSphere Medical and Ciné-Med implement a mechanism to identify and resolve all conflicts of interest before delivering the educational activity to learners.

Non-Endorsement Statement
MediaSphere Medical and Ciné-Med verify that sound education principles have been demonstrated in developing this educational offering, as evidenced by reviewing its objectives, teaching plan, faculty, and activity evaluation process. MediaSphere Medical and Ciné-Med do not endorse or support the actual opinions or material content presented by the speaker(s) and sponsoring organization.

Commercial Support
The Conference is partially funded through educational grants and sponsorships from multiple companies. Recognition of support is provided on the Industry Partners webpage and will be announced during the conference.

Joint Providership:
MediaSphere Medical, LLC and Ciné-Med

Abstract Competition

8th Annual International Physiology of Pacing Symposium 2024

Share your Research with Colleagues and Leading Experts!

Please submit your abstract of original research for the opportunity to present it at the 8th Annual International Physiology of Pacing Symposium. Clinical studies, basic science investigations, or preclinical studies relevant to conduction system pacing are considered original research. Abstracts must convey original research but can include portions of previous abstracts and/or manuscripts presented elsewhere.

An expert panel will judge submitted abstracts, and the authors of the Top 3 Abstracts will be invited to the Symposium (registration, travel reimbursement, and lodging will be provided).

The authors of the Top 3 Abstracts will be invited to present their research work during the New Science Abstract Presentation Session on Friday, October 25, 2024, at the . The winning abstract author will receive a $1,000 prize and a plaque to commemorate their outstanding achievement, and the runners-up will also each receive a $500 prize. Additionally, each of the 3 top authors will have the opportunity to have their full abstract or research letter published within Heart Rhythm.

Download Application >>

Abstracts Submission Policy and Guideline Summary.
Before submission, please review the following policy and travel, accommodations, and reimbursement information.

Submission Deadline: September 10, 2024.

Abstract Composition: Abstracts should convey original research in clinical studies, basic science investigations, or preclinical studies relevant to conduction system pacing. Portions of previous abstracts and/or manuscripts presented elsewhere are permitted.
The abstract character limit is 2,200, including spaces (approximately 300 - 500 words). Figures and/or tables may be included, but they count for 500 characters each.
Abstracts must be submitted in English.
Please do not include your Title or Author information in the body of your abstract; these should only be included in the accompanying application.
Notification: A decision on your abstract will be provided towards the latter part of September directly to the email address used for submission.
Exclusions: Paid employees of companies who manufacture and/or distribute medical devices, equipment, or pharmaceutical agents are not eligible to participate.
In-person attendance required: The Abstract Finalists must attend the Symposium on-site to present their work, as virtual participation is not permitted. Those who submit the top 3 abstracts will receive a scholarship for registration, a 1-night hotel stay at the Crystal Gateway Marriott, and coach/economy air travel reimbursement. Please review the Travel, Accommodations, and Reimbursement section below.

Abstract Finalists Participation Details
The following information provides essential details for the authors of the top abstracts. A member of MediaSphere Medical will coordinate all facets of participation, including travel and lodging arrangements.

Top 3 Abstracts Authors
The authors of the Top 3 Abstracts will be invited to present their research work during the New Science Abstract Presentation Session on Friday, October 25, 2024, at the Crystal Gateway Marriott. The winning abstract author will receive a $1,000 prize and a plaque to commemorate their outstanding achievement, and the runners-up will also each receive a $500 prize. Additionally, each of the 3 top authors will have the opportunity to have their full abstract or research letter published within Heart Rhythm.

Your developed presentation should not exceed 5 minutes; allow a few minutes for a post-presentation discussion among the program directors.
Please bring your presentation to the Crystal Gateway Marriott on a flash drive.
You will present directly from the podium through the master conference laptop, and a brief post-lecture discussion involving the Session Chairs will occur immediately after your lecture.
The overall winner of the abstract competition will be announced after the Program Directors have deliberated briefly.

Travel, Accommodations, and Reimbursement

The organizer, MediaSphere Medical, will reimburse the top 3 abstract authors for coach airfare up to $450 USD with the required documentation and reimbursable airport transportation.
Recipients who choose to drive to the Conference will be reimbursed for car mileage (at the prevailing government rate).

Hotel Room Reservations

The Conference Organizer will pay for 1 night at the Crystal Gateway Marriott on Thursday, October 24th.

Non-reimbursable expenses

Local transportation
Meals outside of course functions
Guests' travel and expenses
Extra-person charges at the hotel
Cancellation fees imposed by hotel or airline
Miscellaneous expenses

Cancellation Policy

Abstract finalists will be required to submit a cancellation request immediately.
Recipients will not be reimbursed for any expenses—including transportation and hotel cancellation fees—if attendance is canceled.

Registration

Registration
Please join us at the Crystal Gateway Marriott or online in real time for this unsurpassed educational opportunity.

Register >>

In-Person Attendance
Registration fees for the 8th Annual International Physiology of Pacing Symposium are below. Full payment is required at the time of registration. Only registrations accompanied by payment will be accepted. Although walk-ins are welcomed, advanced registration is recommended. In-person attendance permits full symposium session admission, complimentary F&B functions, CME certification, access to exhibit displays, and advanced priority access to the On-Demand Library.

Registration
Please join us at the Crystal Gateway Marriott or online in real time for this unsurpassed educational opportunity.

In-Person Registration Fees	Registration Fees
Physicians Biomedical, Pharmaceutical, or Medical Device Employees Allied Healthcare Professionals *Fellows and Residents	$395 $595 $195 $100

**Attention Fellows and Residents**
Fellows and Residents whose onsite attendance has been confirmed will be refunded their registration fee during check-in.

Location
Crystal Gateway Marriott
1700 Richmond Highway
Arlington, Virginia

Hotel Room Reservations
Crystal Gateway Marriott:A limited number of rooms have been reserved at the Crystal Gateway Marriott at a special group rate of $249 per night per single/double occupancy for Thursday, October 24, 2024. We recommend that you make a reservation as soon as possible. Cut-off date: Thursday, September 26, 2024.

Hotel Room Reservations >>

Reserve By Phone: Call the central reservation at 1-800-393-3680 and reference the Physiology Pacing Symposium.

Register >>

Virtual Attendance in Real-Time
Virtual attendance and engagement in real-time at the 8th Annual International Physiology of Pacing Symposium are made possible through the live-streaming broadcast platform from the convenience of a computer or mobile device. The Symposium will be transmitted in real-time from Crystal Gateway Marriott. Virtual attendance permits access to every session with direct faculty engagement, continuing medical education certificates, and advanced priority access to the On-Demand Library.

Accessing the Live-Stream
Upon successful registration, you will receive a confirmation email with your Unique Live-Stream Digital Pass and instructions on accessing the symposium as a virtual attendee. The Unique Live-Stream Digital Pass provides universal access to the real-time stream across multiple devices.

Virtual Registration Fees	Registration Fees
All Attendees	$150

The 8th Annual International Physiology of Pacing Symposium 2024 agenda will follow Eastern Standard Time. Access the World Clock to find your local time for the live stream.

In-Person and Virtual Attendance Cancellation and Refund Policy
Full refunds will only be given before October 14, 2024. After October 14th, no refunds will be provided. All refund requests should be submitted to This e-mail address is being protected from spambots. You need JavaScript enabled to view it

The course organizers reserve the right to cancel or postpone any course due to unforeseen circumstances. In the event of cancellation or postponement, the course organizers will refund registration fees. Still, they will not be responsible for related costs or expenses to participants, including cancellation fees assessed by hotels, airlines, and travel agencies.

Services for the Disabled
If special arrangements are required for an individual with a disability to attend this meeting, please get in touch with the Course Organizers with the request no later than October 15, 2023, at This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Industry Partners

2024 Industry Partners

Partners In Educational Advancements

The generous support of our industry colleagues makes the 8th Annual International Physiology of Pacing Symposium possible.

Educational Grantors
We gratefully acknowledge our industry partners for their significant and generous educational grant support, which profoundly impacts education.

Medtronic • Boston Scientific • Abbott • Biotronik

Impulse Dynamics • CVRx • Murj

Thank you to our Sponsors!

Platinum
Boston Scientific • Murj

Gold
Abbott • PaceMate

Benefactor
CV Remote Solutions • EBR Systems Inc. • Zoll

Thank you to our Exhibitors!

Abbott

Biotronik

Boston Scientific

Zio by iRhythm

Murj

PaceMate

ZOLL

Partner Institutions
The Summit is supported through educational grants from:

Co-Sponsor